Atıf İçin Kopyala
Erturk E., DEMİR A. G.
ARKIVOC, ss.160-171, 2008 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Basım Tarihi:
2008
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Dergi Adı:
ARKIVOC
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.160-171
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Anahtar Kelimeler:
epoxide, epoxide opening, amino alcohol, iron, solvent-free, green chemistry, HYDROLYTIC KINETIC RESOLUTION, AROMATIC-AMINES, EFFICIENT METHOD, MESO-EPOXIDES, ASYMMETRIC AMINOLYSIS, ALCOHOLS, MILD, CLEAVAGE, TRIFLATE, ANILINES
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Orta Doğu Teknik Üniversitesi Adresli:
Evet
Özet
Non-hygroscopic, non-toxic, and readily available iron(III) trifluoroacetate [Fe(O2CCF3)(3)] was found to be a highly regioselective catalyst for the ring opening of a wide variety of epoxides with diverse amines under solvent-free conditions. The stereospecific ring opening of (R)-styrene oxide (4) with p-anisidine (2b) in the presence of 1 mol% of Fe(O2CCF3)(3) gave 2-(p-methoxyphenyl-amino)-2-phenylethanol (5b) in enantiopure form (> 99 % ee) within 60 minutes.