One-pot synthesis of N-substituted 2-methyl-4,5,6,7-tetrahydroindole derivatives


Tanyeli C. , Akhmedov I., Yazicioglu E.

TETRAHEDRON LETTERS, cilt.45, sa.52, ss.9627-9629, 2004 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Konu: 52
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.tetlet.2004.10.145
  • Dergi Adı: TETRAHEDRON LETTERS
  • Sayfa Sayıları: ss.9627-9629

Özet

We describe the preliminary results of one-pot syntheses of various N-substituted 2-methyl-4,5,6,7-tetrahydroindole derivatives from 2-(2-bromoailyl)cyclohexanone and the corresponding primary amines in good yields. Aliphatic amines were directly converted to tetrahydroindoles, whereas aromatic amines needed an extra base treatment step to complete the transformation. (C) 2004 Elsevier Ltd. All rights reserved.