New chiral synthon from the PLE catalyzed enantiomeric separation of 6-acetoxy-3-methylcyclohex-2-en-1-one

Tanyeli C., Demir A., Dikici E.

TETRAHEDRON-ASYMMETRY, cilt.7, sa.8, ss.2399-2402, 1996 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 8
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1016/0957-4166(96)00296-0
  • Dergi Adı: TETRAHEDRON-ASYMMETRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Sayfa Sayıları: ss.2399-2402
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

(+/-)-6-Acetoxy-3-methylcyclohex-2-en-1-one was resolved by PLE catalyzed hydrolysis to afford (+)-6-hydroxy-3-methylcyclohex-2-en-1-one in >95% e.e. (+)-6-Hydroxy-3-methylcyclohex-2-en-1-one was transformed to its (S)-O-acetyllactyl ester derivative to determine the e.e. %. Copyright (C) 1996 Elsevier Science Ltd