Efficient synthesis of 1-alkoxycarbonyl-methyl-2-alkylpyrroles from dichloro- and methoxychloropropylalkyl ketones

Gadzhili R., Nadzhafova R., Sesenoglu O.

TURKISH JOURNAL OF CHEMISTRY, vol.26, no.3, pp.379-383, 2002 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 3
  • Publication Date: 2002
  • Journal Name: TURKISH JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.379-383
  • Middle East Technical University Affiliated: No

Abstract

The condensation reaction of 2,3-dichloropropyl- and 2-methoxy-3-chloropropyl alkyl ketones with alkyl 2-aminoacetate salts leads to 1-alkoxy-carbonylmethyl-2-alkylpyrroles. These compounds, with various bases, gave 1-carbamoylmethyl-, 1-dialkylaminocarbonylmethyl-, 1-carbazoyl methyl-2-alkylpyrroles and potassium salt of 2-alkyl-pyrrolyl-1-acetic acid.