Evaluation of bioreductive activation of anticancer drugs idarubicin and mitomycin C by NADH-cytochrome b5 reductase and cytochrome P450 2B4
XENOBIOTICA, vol.43, no.3, pp.263-275, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 43 Issue: 3
- Publication Date: 2013
- Doi Number: 10.3109/00498254.2012.715212
- Journal Name: XENOBIOTICA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.263-275
- Middle East Technical University Affiliated: No
Abstract
1. This study attempted to investigate the ability of microsomal NADH-cytochrome b5 reductase and cytochrome P450 2B4 to reductively activate idarubicin and mitomycin C.