Co-delivery of Doxorubicin and D-alpha-Tocopherol Polyethylene Glycol 1000 Succinate by Magnetic Nanoparticles

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Metin E., MUTLU P., GÜNDÜZ U.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.18, no.8, pp.1138-1147, 2018 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 18 Issue: 8
• Publication Date: 2018
• Doi Number: 10.2174/1871520618666180313154724
• Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1138-1147
• Middle East Technical University Affiliated: Yes

Abstract

Background: Although conventional chemotherapy is the most common method for cancer treatment, it has several side effects such as neuropathy, alopecia and cardiotoxicity. Since the drugs are given to body systemically, normal cells are also affected, just like cancer cells. However, in recent years, targeted drug delivery has been developed to overcome these drawbacks.