Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase

Demir A., Dunnwald T., Iding H., Pohl M., Muller M.

TETRAHEDRON-ASYMMETRY, cilt.10, sa.24, ss.4769-4774, 1999 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 24
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0957-4166(99)00516-9
  • Dergi Adı: TETRAHEDRON-ASYMMETRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.4769-4774
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Aromatic aldehydes are converted into benzoins by benzoylformate decarboxylase catalyzed C-C bond formation. The reaction affords (R)-benzoins with high enantiomeric excess and in good chemical yields. A broad range of aromatic aldehydes can be used as substrates in aqueous buffer or buffer/DMSO-solutions. (C) 2000 Elsevier Science Ltd. All rights reserved.