Imaging of liposomes by scanning tunneling microscopy
ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY, vol.24, no.5, pp.525-531, 1996 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 24 Issue: 5
- Publication Date: 1996
- Doi Number: 10.3109/10731199609117444
- Journal Name: ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Compendex, EMBASE, MEDLINE, Directory of Open Access Journals
- Page Numbers: pp.525-531
- Middle East Technical University Affiliated: Yes
Abstract
In this study, unilamellar and multilamellar liposomes consisting of dipalmitoylphosphatidylcholine, cholesterol and dicetylphosphate were prepared. Scanning tunneling microscopy images of these liposomes on highly oriented pyrolytic graphite surfaces were obtained. It was observed that scanning tunnelling microscopy can be succesfully used for high-resolution, three-dimensional structure analysis of liposomes under very mild conditions.