Investigation of the Processing of Noun and Verb Words with fMRI in Patients with Schizophrenia

Nazlı Ş. B., Koçak O. M., Kırkıcı B., Sevindik M., Kokurcan A.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.57, sa.1, ss.9-14, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.29399/npa.23521
  • Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, Psycinfo, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.9-14
  • Anahtar Kelimeler: Language in schizophrenia, fMRI, lexical decision task, LANGUAGE, SCALE, RELIABILITY, VALIDITY, AREA
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Introduction: Action naming is reported to be more damaged in patients with schizophrenia than object naming. Aim of this study is to understand the cortical mechanism underlying the negative symptoms seen in patients with schizophrenia such as inactivity, restricted behavioral repertoire, by using functional MRI (fMRI) to determine whether the action origin words have a different representation in the brain regions of patients with schizophrenia and healthy individuals. Our hypothesis is that restriction in the repertoire of movement and behavior and the failure of words of "action" than words of "object" are interrelated through the same cortical mechanisms. If this hypothesis is correct, the reason for not taking action in patients with schizophrenia may be improper definition of the action (verb).