Effects of biomimetic synthesis route and sintering temperature on physicochemical, microstructural, and mechanical properties of hydroxyapatite

Kaya Y., Jodati H., Evis Z.

Journal of the Australian Ceramic Society, cilt.57, sa.4, ss.1117-1129, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s41779-021-00609-x
  • Dergi Adı: Journal of the Australian Ceramic Society
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Communication Abstracts, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.1117-1129
  • Anahtar Kelimeler: Hydroxyapatite, Biomimetic synthesis, Simulated body fluid, Microstructure, CALCIUM-DEFICIENT HYDROXYAPATITE, IN-VITRO BIOACTIVITY, BONE TISSUE, SUBSTITUTED HYDROXYAPATITE, HYDROTHERMAL SYNTHESIS, DOPED HYDROXYAPATITES, BIOLOGICAL-PROPERTIES, PARTICLE-SIZE, SCAFFOLDS, FABRICATION
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

© 2021, Australian Ceramic Society.Biomimetic synthesis of bioceramics using simulated body fluid (SBF) is a route to produce biomaterials with a more suitable microstructure and characteristics required for bone defect treatments. As matter of fact, the biomimetic method allows us to imitate the natural environment needed for the synthesis of bone-like materials, such as hydroxyapatite (HA). In this study, biomimetic HA was successfully synthesized through the microwave-assisted method by the employment of SBF in different ratios with water as a solvent for precursors. Later, synthesized powders were sintered at four different temperatures (700°C, 900°C, 1100°C, and 1300°C), and their physicochemical properties, as well as microstructure and microhardness, were examined. Results depicted that synthesized biomimetic HAs are highly pure. They experienced larger particle size growth when exposed to higher sintering temperatures when compared to non-biomimetic HA. Moreover, density (porosity) and microhardness of biomimetic HAs, especially the one that used 100% SBF as a solvent for calcium precursor and sintered at 900°C, had closer value to the natural human femur and could serve as promising candidates for bone defect treatment application.