A novel synthesis of optically active alpha-amino acids


Demir A.

PURE AND APPLIED CHEMISTRY, vol.69, no.1, pp.105-108, 1997 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 69 Issue: 1
  • Publication Date: 1997
  • Doi Number: 10.1351/pac199769010105
  • Journal Name: PURE AND APPLIED CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.105-108

Abstract

A new enantioselective synthesis of alpha- amino acids are described in which the key step is the enantioselective reduction of E, and Z furyl ketone oxime ethers with chiral boron complexes. The chirality of amino acid is fully controlled by appropriate choice of geometrical isomer of the oxime ether.