Early osteoblastic activity on TiO(2)thin films decorated with flower-like hierarchical Au structures


Kalantzis S., Veziroglu S., Kohlhaas T., Floerke C., Mishra Y. K. , Wiltfang J., ...More

RSC ADVANCES, vol.10, no.48, pp.28935-28940, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 48
  • Publication Date: 2020
  • Doi Number: 10.1039/d0ra05141a
  • Journal Name: RSC ADVANCES
  • Journal Indexes: Science Citation Index Expanded, Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, Compendex, Metadex, Directory of Open Access Journals
  • Page Numbers: pp.28935-28940

Abstract

Titanium alloys are the most commonly used dental and orthopedic implant materials due to their proven biocompatibility and mechanical properties. The native oxide layer (TiO(2)layer) formed on such Ti-based implants acts as the self-protecting layer against possible ion release. Increasing the oxide layer thickness further on such TiO(2)implants even opens the triggering of the osseointegration process if the oxide layer is having a certain degree of roughness, preferably higher. This work reports a novel photocatalytic patterning of sputter deposited TiO(2)layers with flower-like Au structures to enhance the early osteoblastic activity. The prepared hierarchical Au structures, composed of micro- and nanoscale features on the top, lead to improved number of filopodia formation. This suggest that proposed Au-TiO(2)surface may foster the cell attachment and as well as cell proliferation.