Targeted silencing of Survivin in cancer cells by siRNA loaded chitosan magnetic nanoparticles

ÜNSOY G., GÜNDÜZ U.

EXPERT REVIEW OF ANTICANCER THERAPY, cilt.16, sa.7, ss.789-797, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 7
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1080/14737140.2016.1184981
  • Dergi Adı: EXPERT REVIEW OF ANTICANCER THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.789-797
  • Anahtar Kelimeler: Chitosan, magnetic nanoparticles, survivin siRNA, targeted drug delivery, doxorubicin resistant MCF-7 cells, DRUG-RESISTANCE, BREAST-CANCER, GENE DELIVERY, DOXORUBICIN, STABILITY, RELEASE
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Background: The aim of this study was to silence Survivin expression, related with drug-resistance, via siRNA-loaded CS-MNPs.