Targeted silencing of Survivin in cancer cells by siRNA loaded chitosan magnetic nanoparticles

ÜNSOY G., GÜNDÜZ U.

EXPERT REVIEW OF ANTICANCER THERAPY, vol.16, no.7, pp.789-797, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 7
  • Publication Date: 2016
  • Doi Number: 10.1080/14737140.2016.1184981
  • Journal Name: EXPERT REVIEW OF ANTICANCER THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.789-797
  • Keywords: Chitosan, magnetic nanoparticles, survivin siRNA, targeted drug delivery, doxorubicin resistant MCF-7 cells, DRUG-RESISTANCE, BREAST-CANCER, GENE DELIVERY, DOXORUBICIN, STABILITY, RELEASE
  • Middle East Technical University Affiliated: Yes

Abstract

Background: The aim of this study was to silence Survivin expression, related with drug-resistance, via siRNA-loaded CS-MNPs.