Genome wide evolutionary analyses reveal serotype specific patterns of positive selection in selected Salmonella serotypes


Creative Commons License

Soyer Y. , Orsi R. H. , Rodriguez-Rivera L. D. , Sun Q., Wiedmann M.

BMC EVOLUTIONARY BIOLOGY, vol.9, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9
  • Publication Date: 2009
  • Doi Number: 10.1186/1471-2148-9-264
  • Title of Journal : BMC EVOLUTIONARY BIOLOGY

Abstract

Background: The bacterium Salmonella enterica includes a diversity of serotypes that cause disease in humans and different animal species. Some Salmonella serotypes show a broad host range, some are host restricted and exclusively associated with one particular host, and some are associated with one particular host species, but able to cause disease in other host species and are thus considered "host adapted". Five Salmonella genome sequences, representing a broad host range serotype (Typhimurium), two host restricted serotypes (Typhi [two genomes] and Paratyphi) and one host adapted serotype (Choleraesuis) were used to identify core genome genes that show evidence for recombination and positive selection.