Clean and efficient microwave-solvent-free conversion of homochiral amines, alpha-amino alcohols and alpha-amino acids to their chiral 2-substituted pyrrole derivatives


Aydogan F., Demir A.

TETRAHEDRON, cilt.61, ss.3019-3023, 2005 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 61 Konu: 12
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.tet.2005.01.120
  • Dergi Adı: TETRAHEDRON
  • Sayfa Sayıları: ss.3019-3023

Özet

Efficient synthesis of 1,2-disubstituted homochiral pyrroles has been achieved by a two-component coupling of chloroenones and amine compounds on the surface of silica gel without any solvent under microwave irradiation. (c) 2005 Elsevier Ltd. All rights reserved.