Clean and efficient microwave-solvent-free conversion of homochiral amines, alpha-amino alcohols and alpha-amino acids to their chiral 2-substituted pyrrole derivatives

Aydogan, F; Demir, AYHAN

doi:10.1016/j.tet.2005.01.120

Clean and efficient microwave-solvent-free conversion of homochiral amines, alpha-amino alcohols and alpha-amino acids to their chiral 2-substituted pyrrole derivatives

Aydogan F., Demir A.

TETRAHEDRON, cilt.61, sa.12, ss.3019-3023, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 61 Sayı: 12
Basım Tarihi: 2005
Doi Numarası: 10.1016/j.tet.2005.01.120
Dergi Adı: TETRAHEDRON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.3019-3023
Anahtar Kelimeler: pyrrole, microwave, silica gel, chloroenone, PHOTOOXYGENATION, ACYLATION, CHEMISTRY, SYSTEMS
Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Efficient synthesis of 1,2-disubstituted homochiral pyrroles has been achieved by a two-component coupling of chloroenones and amine compounds on the surface of silica gel without any solvent under microwave irradiation. (c) 2005 Elsevier Ltd. All rights reserved.