Meso-piperidine linked bodipys: Synthesis, fluorescent properties and biological evaluation

Ecik E. T., Kazan H. H., Sengul I. F., KANDEMİR H., Cosut B.

JOURNAL OF LUMINESCENCE, cilt.205, ss.258-264, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 205
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jlumin.2018.09.024
  • Dergi Adı: JOURNAL OF LUMINESCENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.258-264
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

The synthesis and characterization of meso-piperidine linked Bodipy starting from 4-(2-(piperidine-1-yl)ethoxy) benzaldehyde was described. Meso-piperidine linked Bodipy was subsequently used for the construction of distyryl-piperidine-Bodipy and distyryl-morpholine-Bodipy via Knoevenagel type reaction. The photophysical properties including molar extinction coefficient, fluorescence lifetime and fluorescence quantum yield of Bodipys were investigated in ethanol solution. The targeted compounds were also assessed in live cell imaging and cytotoxicity studies by using breast cancer cell line, MCF-7 in vitro.