A new and stereospecific synthesis of an inositol analogue: bis-homoinositol


Kara Y., Balci M.

TETRAHEDRON, cilt.59, ss.2063-2066, 2003 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 59 Konu: 12
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0040-4020(03)00209-6
  • Dergi Adı: TETRAHEDRON
  • Sayfa Sayıları: ss.2063-2066

Özet

The photooxygenation of trans-8-(acetyloxy)bicyclo[4.2.0]octa-2,4-dien-7-yl acetate afforded the bicyclic endoperoxide. Reduction of the endoperoxide with thiourea followed by acetylation gave the corresponding tetraacetate. The KMnO4 oxidation of the tetraacetate followed by acetylation gave dihydroxytetraacetate Ammonolysis of tetraacetate afforded the bis-homoinositol, bicyclo[4.2.0]octane-2,3,4,5,7,8-hexol. (C) 2003 Elsevier Science Ltd. All rights reserved.