LIVER INTERNATIONAL, vol.35, no.3, pp.846-853, 2015 (Journal Indexed in SCI)
Article / Article
Title of Journal :
hepatitis B infection, hepatitis delta infection, interferon lambda 3, interleukin 28 B, single nucleotide polymorphisms, GENOME-WIDE ASSOCIATION, NATURAL-HISTORY, CHRONIC HBV, HEPATOCELLULAR-CARCINOMA, ANTIGEN SEROCLEARANCE, INTERFERON-ALPHA, HLA-DP, VIRUS, IL28B, DELTA
Background & AimsAim of this study was to investigate whether a potential association exists between several single nucleotide polymorphisms (SNPs) of the IL-28B gene (rs12979860, rs1188122, rs8099917, rs8105790, rs12980275) and HBsAg persistence. Further, a potential effect on the development of HBeAg-negative CHB vs. inactive HBsAg carrier state was assessed in a genotype D HBV cohort. A cohort of chronic HDV patients was also used to see if they behave differently compared to chronic HBV patients.