Synthesis of ferrocenyl pyrazoles by the reaction of (2-formyl-1-chlorovinyl)ferrocene with hydrazines

Zora M., Goermen M.

JOURNAL OF ORGANOMETALLIC CHEMISTRY, cilt.692, sa.22, ss.5026-5032, 2007 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 692 Sayı: 22
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.jorganchem.2007.07.029
  • Dergi Adı: JOURNAL OF ORGANOMETALLIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5026-5032
  • Anahtar Kelimeler: ferrocene, ferrocenyl, pyrazole, hydrazine, hydrazinium salt, hydrazide, propenal, density functional theory, B3LYP, ESTROGEN-RECEPTOR MODULATORS, ONE-POT SYNTHESIS, ACTIVITY IN-VITRO, REGIOSELECTIVE SYNTHESIS, ANTIMALARIAL ACTIVITY, ORGANOMETALLIC ANALOG, DIACETYLENIC KETONES, CRYSTAL-STRUCTURES, ACID, COMPLEXES
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Synthesis of ferrocenyl-substituted pyrazoles via the reaction between (2-formyl-1-chlorovinyl)ferrocene and hydrazine derivatives is described. Depending upon the substitution pattern of hydrazine, the reaction affords 1-alkyl/aryl-5-ferrocenylpyrazoles and/or 1-alkyl/ aryl-3-ferrocenylpyrazoles. The reaction appears to be general for a variety of hydrazine derivatives. (c) 2007 Elsevier B.V. All rights reserved.