ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, vol.35, no.11, pp.2050-2062, 2011 (SCI-Expanded)
Article / Article
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Ethanol Abuse, Ethanol Withdrawal, Rats, Hippocampus, FT-IR Spectroscopy, TRANSFORM-INFRARED-SPECTROSCOPY, PROTEIN SECONDARY STRUCTURE, PHYSICAL-DEPENDENCE, LIPID-PEROXIDATION, ALCOHOL, BRAIN, INDUCTION, LIVER, TOLERANCE, MEMORY
Middle East Technical University Affiliated:
Background: The numerous adverse effects of ethanol abuse and ethanol withdrawal on biological systems are well documented. Conversely, the understanding of the molecular mechanisms underlying these pathological effects is still incomplete. This study was undertaken to investigate the effects of short-term chronic ethanol administration and ethanol withdrawal on the molecular structure and function of hippocampal tissue, a brain region important for mnemonic processes and known to be highly susceptible to ethanol intoxication.