Parkinsonian Rest Tremor Is Associated With Modulations of Subthalamic High-Frequency Oscillations

Hirschmann J., Butz M., Hartmann C. J., Hoogenboom N., ÖZKURT T. E., Vesper J., ...More

MOVEMENT DISORDERS, vol.31, no.10, pp.1551-1559, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 10
  • Publication Date: 2016
  • Doi Number: 10.1002/mds.26663
  • Journal Name: MOVEMENT DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1551-1559
  • Keywords: high-frequency oscillations, Parkinson's disease, tremor, deep brain stimulation, subthalamic nucleus, DEEP BRAIN-STIMULATION, FAST RIPPLES, NUCLEUS, BETA, NETWORK, PATHOPHYSIOLOGY, SYNCHRONIZATION, MECHANISMS, SPIKING, LOOP
  • Middle East Technical University Affiliated: Yes

Abstract

BackgroundHigh frequency oscillations (>200 Hz) have been observed in the basal ganglia of PD patients and were shown to be modulated by the administration of levodopa and voluntary movement.