Akademik Veri Yönetim Sistemi
Challenges in Rhinology, Springer International Publishing Ag, ss.501-517, 2020
The development and use of personalized medicine have an increasing importance in patient care. Numerical simulations of various biological phenomena have and continue to enable doctors and medical specialists to diagnose patients and understand how practical and effective treatment can be. The paths to patient-specific diagnosis and preoperative planning are slowly being paved and with immense success. Proof of this lies in the major developments made in medical software that have enabled accurate three-dimensional (3D) models of the human organs to be generated for use in analysis, ensuring accurate results. Also, advancements in technology have enabled simulation of surgeries where professionals can make cuts, test out different implant sizes and do much more to the models of organs. This helps the medical practitioner find out the effects of the procedure beforehand by performing analysis of the modified model. Breathing is a dynamic process between inhaled air, mucosal surfaces and the alveoli. Within the nasal cavity, there are changes of airflow and pressure occurring during the respiratory cycle, as well as exchanges of heat and humidity, and important immune responses to inhaled antigens and allergens. However, evaluation of nasal function with anterior rhinoscopy, nasal endoscopy and/or paranasal CT scan is usually insufficient to make proper assessment of airflow, air-surface interaction and olfaction. In this chapter, the focus is placed on personalized nasal surgery and how the procedure has been enhanced with numerical simulations of respiration. We will venture into details of normal physiologic respiration through the nose and how numerical simulations help as a predictive tool.