Rapid wall shear stress prediction for aortic aneurysms using deep learning: a fast alternative to CFD

Faisal M. A. A., Mutlu O., Mahmud S., Tahir A., Chowdhury M. E. H., Bensaali F., ...More

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, vol.63, no.7, pp.2173-2190, 2025 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 7
  • Publication Date: 2025
  • Doi Number: 10.1007/s11517-025-03311-3
  • Journal Name: MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, ABI/INFORM, Applied Science & Technology Source, BIOSIS, Biotechnology Research Abstracts, Business Source Elite, Business Source Premier, CINAHL, Compendex, Computer & Applied Sciences, INSPEC
  • Page Numbers: pp.2173-2190
  • Keywords: Abdominal aortic aneurysm, Artificial intelligence, Computational fluid dynamics, Deep learning, Hemodynamics, Neural network
  • Middle East Technical University Affiliated: Yes

Abstract

Aortic aneurysms pose a significant risk of rupture. Previous research has shown that areas exposed to low wall shear stress (WSS) are more prone to rupture. Therefore, precise WSS determination on the aneurysm is crucial for rupture risk assessment. Computational fluid dynamics (CFD) is a powerful approach for WSS calculations, but they are computationally intensive, hindering time-sensitive clinical decision-making. In this study, we propose a deep learning (DL) surrogate, MultiViewUNet, to rapidly predict time-averaged WSS (TAWSS) distributions on abdominal aortic aneurysms (AAA). Our novel approach employs a domain transformation technique to translate complex aortic geometries into representations compatible with state-of-the-art neural networks. MultiViewUNet was trained on 23 real and 230 synthetic AAA geometries, demonstrating an average normalized mean absolute error (NMAE) of just 0.362% in WSS prediction. This framework has the potential to streamline hemodynamic analysis in AAA and other clinical scenarios where fast and accurate stress quantification is essential.