Differential modulation of STN-cortical and cortico-muscular coherence by movement and levodopa in Parkinson's disease


Hirschmann J., ÖZKURT T. E. , Butz M., Homburger M., Elben S., Hartmann C. J. , ...More

NEUROIMAGE, vol.68, pp.203-213, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68
  • Publication Date: 2013
  • Doi Number: 10.1016/j.neuroimage.2012.11.036
  • Journal Name: NEUROIMAGE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.203-213
  • Keywords: Parkinson's disease, Oscillations, MEG, Coherence, STN, Deep brain stimulation, DEEP BRAIN-STIMULATION, TASK-DEPENDENT MODULATION, HUMAN SUBTHALAMIC NUCLEUS, SPACE SEPARATION METHOD, HUMAN BASAL GANGLIA, CEREBRAL-CORTEX, PATHOLOGICAL SYNCHRONIZATION, BETA-DESYNCHRONIZATION, MOTOR-PERFORMANCE, BAND OSCILLATIONS
  • Middle East Technical University Affiliated: Yes

Abstract

Previous research suggests that oscillatory coupling between cortex, basal ganglia and muscles plays an important role in motor behavior. Furthermore, there is evidence that oscillatory coupling is altered in patients with movement disorders such as Parkinson's disease (PD).