In order to investigate preference responses for foreground-background color relationships, 85 university undergraduates in Ankara, Turkey, viewed 6 background colors (red, yellow, green, cyan, blue, and magenta) on which color squares of differing hues, saturations, and brightnesses were presented. All the background colors had maximum brightness (100%) and maximum saturation (100%). Subjects were asked to show the color square they preferred on the presented background color viewed through a computer monitor. The experimental setup consisted of a computer monitor located in a windowless room, illuminated with cove lighting, The findings of the experiment show that the brightness 100%-saturation100% range is significantly preferred the most (p-value<0.03). Thus, color squares that are most saturated and brightest are preferred on backgrounds of most saturated and brightest colors. Regardless of the background colors viewed, the subjects preferred blue the most (p-value<0.01). Findings of the study are also discussed with pertinent research on the field. Through this analysis, an understanding of foreground-background color relationships in terms of preference is sought.