Atıf İçin Kopyala
Yalcin S., MUTLU P., Cetin T., Sarper M., Ozgur G., Avcu F.
TURKISH JOURNAL OF HEMATOLOGY, cilt.32, sa.4, ss.311-316, 2015 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
32
Sayı:
4
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Basım Tarihi:
2015
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Doi Numarası:
10.4274/tjh.2014.0126
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Dergi Adı:
TURKISH JOURNAL OF HEMATOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
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Sayfa Sayıları:
ss.311-316
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Anahtar Kelimeler:
1L-18, Chronic lymphocytic leukemia, Chronic myelogenous leukemia, Single nucleotide polymorphisms, NORTH INDIAN POPULATION, PROINFLAMMATORY CYTOKINE, PROSTATE-CANCER, IL-18, EXPRESSION, CARCINOMA, RECEPTOR, CELLS, ASSOCIATION, SUSCEPTIBILITY
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Orta Doğu Teknik Üniversitesi Adresli:
Evet
Özet
Objective: Interleuldn-18 (IL-18) is a cytokine that belongs to the IL-1 superfamily and is secreted by various immune and nonimmune cells. Evidence has shown that 1L-18 has both anticancer and procancer effects. The aim of this study was to evaluate the relationship between IL-18 gene polymorphisms and susceptibility to chronic lymphocytic leukemias (CLL) and chronic myelogenous leukemias (CML) in Turkish patients.