Development of a Reconstructed Cornea from Collagen-Chondroitin Sulfate Foams and Human Cell Cultures

Vrana, N.; Builles, Nicolas; Justin, Virginie; Bednarz, Jurgen; Pellegrini, Graziella; Ferrari, Barbara; Damour, Odile; Hulmes, David; Hasirci, VASIF

doi:10.1167/iovs.07-1599

Development of a Reconstructed Cornea from Collagen-Chondroitin Sulfate Foams and Human Cell Cultures

Vrana N. E., Builles N., Justin V., Bednarz J., Pellegrini G., Ferrari B., ...Daha Fazla

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, cilt.49, sa.12, ss.5325-5331, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 49 Sayı: 12
Basım Tarihi: 2008
Doi Numarası: 10.1167/iovs.07-1599
Dergi Adı: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.5325-5331
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

PURPOSE. To develop an artificial cornea, the ability to coculture the different cell types present in the cornea is essential. Here the goal was to develop a full-thickness artificial cornea using an optimized collagen-chondroitin sulfate foam, with a thickness close to that of human cornea, by coculturing human corneal epithelial and stromal cells and transfected human endothelial cells.