Akademik Veri Yönetim Sistemi
PACIFIC JOURNAL OF OPTIMIZATION, cilt.6, sa.2, ss.319-340, 2010 (SCI-Expanded)
In this paper we survey recent advances and mathematical foundations of regulatory networks. We explain their interdisciplinary implications with special regard to Operational Research and financial sciences and introduce the so-called eco-finance networks. These networks, originally developed in the context of modeling and prediction of gene-expression patterns, have proved to provide a conceptual framework for the modeling of dynamical systems with respect to errors and uncertainty as well as the influence of certain environmental items. Given the noise-prone measurement data we extract nonlinear differential equations to describe and investigate the interactions and regulating effects between the data items of interest and the environmental items. In particular, these equations reflect data uncertainty by the use of interval arithmetics and comprise unknown parameters resulting in a wide variety of the model. For an identification of these parameters Chebychev approximation and generalized semi-infinite optimization are applied. In addition, the time-discrete counterparts of the nonlinear equations are introduced and their parametrical stability is investigated by a combinatorial algorithm which detects the region of parameter stability. We analyze the structural stability of the regulatory networks, we discuss a modeling by stochastic differential equations and explain how spline regression applied in an additive model could be integrated into our analysis. We conclude with two examples for eco-finance networks in the fields of CO2-emissions-control and portfolio Optimization for natural gas transportation systems.