Purpose Integrating ontologies with process modeling has gained increasing attention in recent years since it enhances data representations and makes it easier to query, store and reuse knowledge at the semantic level. The authors focused on a process and ontology integration approach by extracting the activities, roles and other concepts related to the process models from organizational sources using natural language processing techniques. As part of this study, a process ontology population (PrOnPo) methodology and tool is developed, which uses natural language parsers for extracting and interpreting the sentences and populating an event-driven process chain ontology in a fully automated or semi-automated (user assisted) manner. The purpose of this paper is to present applications of PrOnPo tool in different domains. Design/methodology/approach A multiple case study is conducted by selecting five different domains with different types of guidelines. Process ontologies are developed using the PrOnPo tool in a semi-automated and fully automated fashion and manually. The resulting ontologies are compared and evaluated in terms of time-effort and recall-precision metrics. Findings From five different domains, the results give an average of 70 percent recall and 80 percent precision for fully automated usage of the PrOnPo tool, showing that it is applicable and generalizable. In terms of efficiency, the effort spent for process ontology development is decreased from 250 person-minutes to 57 person-minutes (semi-automated). Originality/value The PrOnPo tool is the first one to automatically generate integrated process ontologies and process models from guidelines written in natural language.