IN VITRO DEGRADATION AND BIOACTIVITY OF ANTIBACTERIAL CHROMIUM DOPED O-TRICALCIUM PHOSPHATE BIOCERAMICS

Alshemary A. Z., Muhammed Y., Salman N. A., Hussain R., Motameni A., GÜRBÜZ R., ...Daha Fazla

CERAMICS-SILIKATY, cilt.66, sa.3, ss.347-353, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.13168/cs.2022.0030
  • Dergi Adı: CERAMICS-SILIKATY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Chemical Abstracts Core, Communication Abstracts, Compendex, Metadex, Directory of Open Access Journals, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.347-353
  • Anahtar Kelimeler: O-tricalcium phosphate, Chromium, Microstructure, Bioactivity, Antibacterial, BONE, TEMPERATURE, CERAMICS
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

This study successfully incorporated different chromium ions (Cr3+) fractions into beta-tricalcium phosphate (beta TCP) using the wet-precipitation process aided by microwave radiation. The microstructure analysis of the prepared materials was investigated using XRD and FESEM. The XRD results revealed that the characteristic peaks of Cr-beta TCP materials matched the standard phase of beta TCP crystals. The lattice parameters were decreased with increasing amounts of Cr3+ ions while the degree of crystallinity was increased. The FESEM results revealed that the entire materials were spherical from nano to micro size. The particle growth rate increased significantly as the amount of Cr3+ ions increased. SBF solution was used to test the bioactivity of materials for 14 days at 37 degrees C. The results shows that incorporating Cr3+ ions accelerated the degradation rate of beta TCP and enhanced the deposition rate of the apatite layer. The antibacterial study of beta TCP doped with Cr3+ ions confirmed that the samples were effective as antibacterial agents against Pseudomonas aeruginosa (P. aeruginosa).