JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, vol.4, no.3, pp.347-363, 2020 (Journal Indexed in ESCI)
Article / Article
Title of Journal :
JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
neoplasms, patient-specific modeling, adenocarcinoma of lung, precision medicine, CELLULAR-AUTOMATON MODEL, MATHEMATICAL-MODEL, CANCER-CELLS, CHEMOTAXIS, INVASION, GLUCOSE, HYPOXIA, SIMULATION, DIFFUSION, EVOLUTION
Purpose: Cancer is one of the most complex phenomena in biology and medicine. Extensive attempts have been made to work around this complexity. In this study, we try to take a selective approach; not modeling each particular facet in detail but rather only the pertinent and essential parts of the tumor system are simulated and followed by optimization, revealing specific traits. This leads us to a pellucid personalized model which is noteworthy as it closely approximates existing experimental results.