Distinct oscillatory STN-cortical loops revealed by simultaneous MEG and local field potential recordings in patients with Parkinson's disease


Hirschmann J., Oezkurt T. E., Butz M., Homburger M., Elben S., Hartmann C. J., ...More

NEUROIMAGE, vol.55, no.3, pp.1159-1168, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.1016/j.neuroimage.2010.11.063
  • Journal Name: NEUROIMAGE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1159-1168
  • Keywords: Parkinson's disease, Magnetoencephalography, Subthalamic nucleus, Functional connectivity, Oscillations, Coherence, SIGNAL SPACE SEPARATION, PRIMARY MOTOR CORTEX, SUPERIOR TEMPORAL GYRUS, SUBTHALAMIC NUCLEUS, BASAL GANGLIA, CEREBRAL-CORTEX, RHESUS-MONKEY, FUNCTIONAL CONNECTIVITY, PHYSIOLOGICAL TREMOR, RESTING TREMOR
  • Middle East Technical University Affiliated: No

Abstract

Neuronal oscillations are assumed to play a pivotal role in the pathophysiology of Parkinson's disease (PD). Neurons in the subthalamic nucleus (STN) generate oscillations which are coupled to rhythmic population activity both in other basal ganglia nuclei and cortical areas.