Interplay between 15-lipoxygenase-1 and metastasis-associated antigen 1 in the metastatic potential of colorectal cancer

Tuncer S., ÇAĞATAY S., Keskus A. G., Colakoglu M., KONU KARAKAYALI Ö., BANERJEE S.

CELL PROLIFERATION, vol.49, no.4, pp.448-459, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.1111/cpr.12267
  • Journal Name: CELL PROLIFERATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.448-459
  • Middle East Technical University Affiliated: Yes

Abstract

ObjectivesMetastasis-associated antigen 1 (MTA1) is implicated in metastasis while 15-lipoxygenase-1 (15-LOX-1) reduces cell motility, when re-expressed in colorectal cancer (CRC). We aimed to understand any potential interplay between MTA1 and 15-LOX-1 in CRC metastasis.