Manganese(III) acetate: A versatile reagent in organic chemistry


Demir A. S. , Emrullahoglu M.

CURRENT ORGANIC SYNTHESIS, cilt.4, ss.323-351, 2007 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 4 Konu: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.2174/157017907781369289
  • Dergi Adı: CURRENT ORGANIC SYNTHESIS
  • Sayfa Sayıları: ss.323-351

Özet

Free radical reactions have become increasingly important, as well as a very attractive tool, in organic synthesis within the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Mn(OAc)(3) mediated oxidative free radical reactions have been extensively developed in the last twenty years. Numerous regio-, chemo-, and stereoselective synthetic methods have been developed in both inter- and intramolecular reactions, and have detailed the progress of Mn(OAc)., mediated oxidative free radical reactions since the end of the 19(th) century. The new literature about the new synthetic methods on Mn(OAC)(3) mediated carbon-carbon bond formation and carbon-oxygen bond formation reactions has not been extensively reviewed. The present paper summarizes the recent developments in oxidative free radical reactions mediated by Mn(OAc)(3.) Mn(OAc)(3) mediated reactions of conjugated systems (e.g., alkenes, alkynes, 1,3-alkadienes, 1,3-alkadiynes, 1-alken-3-ynes) with beta-dicarbonyl compounds, Mn(OAc)(3) mediated alkylation, such as the oxidative addition of an aldehyde or ketone to alkenes, Mn(OAc)3 mediated free-radical cyclization of alkenes with active methylene compounds in the presence of oxygen to afford the cyclic peroxides; lactone synthesis by the Mn(OAc)3 mediated oxidative addition of carboxylic acids to alkenes, Mn(OAc)(3) mediated cyclization of alpha-(methythio)acetamides, enamides, and beta-keto carboxamides to afford cyclic products,