The study of genetic and clinicopathological characterisation of Turkish bilateral breast cancer patients

Duzkale N., Teker H. T.

ONCOLOGY IN CLINICAL PRACTICE, cilt.17, sa.1, ss.6-13, 2021 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Konu: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5603/ocp.2020.0026
  • Sayfa Sayıları: ss.6-13


Introduction. Although bilateral breast cancers are a rare condition in the general population, the incidence has increased significantly in BRCA1 and BRCA2 gene carrier breast cancer patients. Besides the genetic susceptibility, many risk factors such as age, first breast cancer diagnosis age, lifestyle, and environmental factors may be effective in the development of this type of cancer. This study aimed to determine BRCA1/2 gene carriage in patients with bilateral breast cancer and to find out the risk factors that may lead to contralateral cancer formation.