Lower limits of detection in speciation analysis by coupling high-performance liquid chromatography and chemical-vapor generation

Arslan Y., Yildirim E., Gholami M., Bakirdere S.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, vol.30, no.4, pp.569-585, 2011 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Review
  • Volume: 30 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.1016/j.trac.2010.11.017
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.569-585
  • Keywords: Arsenic, Atomic absorption spectrometry, Atomic fluorescence spectroscopy, Chemical-vapor generation, Limit of detection, High-performance liquid chromatography, Inductively coupled plasma mass spectrometry, On-line oxidation/reduction, Speciation, Trace element, ATOMIC-ABSORPTION-SPECTROMETRY, PLASMA-MASS-SPECTROMETRY, HPLC-ICP-MS, MICROWAVE-ASSISTED DIGESTION, CLOUD POINT EXTRACTION, DISPLACEMENT SORPTION PRECONCENTRATION, OPTICAL-EMISSION SPECTROMETRY, ONLINE UV-PHOTOOXIDATION, HYDRIDE-GENERATION, FLUORESCENCE SPECTROMETRY


Speciation studies are much more important than total element determination because toxicity of many elements depends on their chemical forms. Nobody can claim that a foodstuff is very dangerous to eat by determining total arsenic due to the possibility that the arsenic could be present in non-toxic forms. Hence, speciation studies are crucial in any matrix relevant to human beings.