FT-IR spectroscopy in diagnosis of diabetes in rat animal model

SEVERCAN F., Bozkurt O., Gurbanov R., Gorgulu G.

JOURNAL OF BIOPHOTONICS, cilt.3, ss.621-631, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 3
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1002/jbio.201000016
  • Dergi Adı: JOURNAL OF BIOPHOTONICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.621-631
  • Anahtar Kelimeler: FT-IR spectroscopy, diagnosis, diabetes, muscle, liver, kidney, membrane, TRANSFORM INFRARED-SPECTROSCOPY, INDUCED INSULIN RESISTANCE, SKELETAL-MUSCLE FIBERS, BLOOD-RETINAL BARRIER, ULTRASTRUCTURAL ALTERATIONS, CLUSTER-ANALYSIS, HEART-DISEASE, MELLITUS, LIVER, METABOLISM
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

In recent years, Fourier Transform Infrared (FT-IR) spectroscopy has had an increasingly important role in the field of pathology and diagnosis of disease states. In the current study, FT-IR spectroscopy together with cluster analysis were used as a diagnostic tool in the discrimination of diabetic samples from control ones in rat kidney plasma membrane apical sides (brush-border membranes), liver microsomal membranes and Extensor digitorum longus (EDL) and Soleus (SOL) skeletal muscle tissues