ULTRASOUND IN OBSTETRICS & GYNECOLOGY, vol.52, no.6, pp.706-714, 2018 (SCI-Expanded)
Article / Review
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
hypertension, metformin, pre-eclampsia, prevention, weight gain, POLYCYSTIC-OVARY-SYNDROME, PREECLAMPSIA, INSULIN, ASPIRIN, PLACEBO, MELLITUS, OUTCOMES, PRETERM, MANAGEMENT, GLYBURIDE
Middle East Technical University Affiliated:
Objective Metformin has been reported to reduce the risk of pre-eclampsia. It is also known to influence soluble fms-like tyrosine kinase-1 level, which correlates significantly with the gestational age at onset and severity of pre-eclampsia. The main aim of this systematic review and meta-analysis of randomized trials was to determine whether metformin use is associated with the incidence of hypertensive disorders of pregnancy (HDP).