Alkylation of l- and d-menthyl pentanoate with (20S)-20-iodomethyl-4 alpha-methyl-5 alpha-pregnane


Demir A.

SYNTHETIC COMMUNICATIONS, cilt.26, ss.4519-4530, 1996 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 26 Konu: 24
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1080/00397919608004775
  • Dergi Adı: SYNTHETIC COMMUNICATIONS
  • Sayfa Sayıları: ss.4519-4530

Özet

The alkylation of l- and d-menthyl valerate with n-hexyl iodide and with (20S)-20-iodomethyl-4 alpha-methyl-5 alpha-pregnane gave modest levels of diastereoselection. The chirality of the ester group favoured slight degree of selectivity. The chiral centers had limited impact on diastereoselectivity.