ANALYTICA CHIMICA ACTA, vol.856, pp.35-45, 2015 (SCI-Expanded)
Article / Article
ANALYTICA CHIMICA ACTA
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Saliva, In vivo sampling, Solid-phase microextraction, Doping substances, Steroids, CHROMATOGRAPHY-MASS SPECTROMETRY, VOLATILE ORGANIC-COMPOUNDS, ALTERNATIVE SPECIMENS, HORMONE MEASUREMENT, METABOLOME, LC/MS/MS, CORTISOL, TOOL, LC
Middle East Technical University Affiliated:
On-site sample preparation is an analytical approach based on direct sampling from the system under investigation. It has the advantage of combining sampling and sample preparation into a single step, thus generally is fast, minimizes the potential sources of error and eliminates the risks for analytes instability. For such analysis solid phase microextraction in thin film geometry (TF-SPME) can provide robust and convenient in vivo sampling, offering in the same time faster analysis and higher extraction recovery (i.e., better sensitivity) due to large surface to volume ratio.