EVALUATION OF THE CHITOSAN-COATING EFFECTIVENESS ON A DENTAL TITANIUM ALLOY IN TERMS OF MICROBIAL AND FIBROBLASTIC ATTACHMENT AND THE EFFECT OF AGING

Kalyoncuoglu U. T., Yilmaz B., Gungor S., EVİS Z., UYAR P., AKCA G., ...Daha Fazla

MATERIALI IN TEHNOLOGIJE, cilt.49, sa.6, ss.925-931, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.17222/mit.2014.239
  • Dergi Adı: MATERIALI IN TEHNOLOGIJE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.925-931
  • Anahtar Kelimeler: chitosan coating, dental implants, Ti6Al4V, HGF-1, P. gingivalis, ANTIMICROBIAL ACTIVITY
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

The aim of this study was to obtain a biocompatible and antimicrobial implant surface by coating Ti6Al4V with chitosan which can be used to create a smooth transmucosal region for a faster and better wound healing and an increased bioactivity. Ti6Al4V plates were first abraded and ultrasonically cleaned and then coated with chitosan. In order to simulate the conditions of an oral environment, a group of coated plates were treated in a thermocycle apparatus. The coatings were evaluated with SEM, EDS, XRD and FTIR spectroscopy. The fibroblastic cell behavior was determined using HGF-1 cells. P. gingivalis was used to assess the effectiveness of chitosan as an antimicrobial coating.