In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration

Tombuloğlu A., Çöpoğlu H., Aydın Son Y. , Güray N. T.

Journal Of Trace Elements In Medicine And Biology, cilt.62, ss.126-130, 2020 (SCI Expanded İndekslerine Giren Dergi)

  • Cilt numarası: 62
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jtemb.2020.126573
  • Dergi Adı: Journal Of Trace Elements In Medicine And Biology
  • Sayfa Sayıları: ss.126-130


Boron is a prominent part of the human diet and one of the essential trace elements for humans.

Dietary boron is mostly transformed into boric acid within the body and has been associated with desirable

health outcomes. Non-dietary resources of boron, such as boron-based drugs and occupational exposure, might

lead to excessive boron levels in the blood and provoke health adversities. The liver might be particularly

sensitive to boron intake with ample evidence suggesting a relation between boron and liver function, although

the underlying molecular processes remain largely unknown.