Stem Cell and Advanced Nano Bioceramic Interactions

Kose S., Kankilic B., Gizer M., Dede E. C., Bayramli E., KORKUSUZ P., ...More

NOVEL BIOMATERIALS FOR REGENERATIVE MEDICINE, vol.1077, pp.317-342, 2018 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 1077
  • Publication Date: 2018
  • Doi Number: 10.1007/978-981-13-0947-2_17
  • Journal Name: NOVEL BIOMATERIALS FOR REGENERATIVE MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.317-342
  • Keywords: Mesenchymal stem cells, bioceramics, hydroxyapatite, tricalcium phosphate, biphasic calcium phosphate, nanotechnology, osteogenic differentiation, regeneration, osteomyelitis, CALCIUM-PHOSPHATE CERAMICS, IN-VITRO, BONE REGENERATION, GROWTH-FACTOR, SUBSTITUTED HYDROXYAPATITES, BIOMEDICAL APPLICATIONS, CARTILAGE DEFECTS, BIOACTIVE GLASSES, STROMAL CELLS, DRUG-RELEASE
  • Middle East Technical University Affiliated: No

Abstract

Bioceramics are type of biomaterials generally used for orthopaedic applications due to their similar structure with bone. Especially regarding to their osteoinductivity and osteoconductivity, they are used as biodegradable scaffolds for bone regeneration along with mesenchymal stem cells. Since chemical properties of bioceramics are important for regeneration of tissue, physical properties are also important for cell proliferation. In this respect, several different manufacturing methods are used for manufacturing nano scale bioceramics. These nano scale bioceramics are used for regeneration of bone and cartilage both alone or with other types of biomaterials. They can also act as carrier for the delivery of drugs in musculoskeletal infections without causing any systemic toxicity.