The effects of local and sustained release of fibroblast growth factor on wound heating in esophageal anastomoses


Fedakar-Senyucel M., Bingo-Kologlu M., Vargun R., Akbay C., Sarac F. N. , Renda N., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.43, sa.2, ss.290-295, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 43 Konu: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.jpedsurg.2007.10.016
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Sayfa Sayıları: ss.290-295

Özet

Background/ Purpose: Postsurgical complications, such as anastomotic leaks in patients with esophageal atresia, have remained unchanged during the last 3 decades. Growth factors enhance healing in several wound-healing models. Therefore, an experimental study was used to evaluate the effects of local and sustained release of basic fibroblast growth factor (FGF) on wound healing in esophageal anastomoses.