New zinc(II)-based catalyst for asymmetric azomethine ylide cycloaddition reactions
ORGANIC LETTERS, cilt.8, sa.21, ss.4687-4690, 2006 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 8 Sayı: 21
- Basım Tarihi: 2006
- Doi Numarası: 10.1021/ol061521f
- Dergi Adı: ORGANIC LETTERS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.4687-4690
- Orta Doğu Teknik Üniversitesi Adresli: Evet
Özet
A new chiral aziridino alcohol ligand for zinc(II)-catalyzed azomethine ylide cycloadditions is described. In the presence of this catalyst, N-arylidene glycine methyl esters react with a variety of dipolarophiles to give substituted pyrrolidines in very good to excellent chemical yields and up to 95% ee. The absolute sense of asymmetric induction appears to be dipolarophile-dependent.