Meso-2,3-dimercaptosuccinic acid: from heavy metal chelation to CdS quantum dots

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Sevinc E., Ertas F. S., Ulusoy G., ÖZEN C., Acar H. Y.

JOURNAL OF MATERIALS CHEMISTRY, cilt.22, sa.11, ss.5137-5144, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 11
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1039/c2jm15741a
  • Dergi Adı: JOURNAL OF MATERIALS CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5137-5144
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

DMSA (meso-2,3-dimercaptosuccinic acid) a prescription drug and a heavy-metal chelating agent, is shown to act both as a sulfur source and a capping agent in the aqueous synthesis of CdS quantum dots under mild conditions. Release of sulfur from DMSA depends on the solution pH and the reaction temperature. Combination of 70 degrees C and pH 7.5 was determined as the best reaction conditions for a well-controlled reaction. Changing the SH/Cd ratio from 2.5 to 7 provides QDs emitting from blue to orange with 6-9% quantum yield with respect to Rhodamine 2B. Viability tests performed with HeLa and MCF-7 cell lines indicate a very low cytotoxicity. Mild reaction conditions and biocompatibility makes these particles valuable candidates for bio applications.