EUROPEAN JOURNAL OF PHARMACOLOGY, vol.784, pp.121-128, 2016 (Journal Indexed in SCI)
Article / Article
Title of Journal :
EUROPEAN JOURNAL OF PHARMACOLOGY
Chitosan, Magnetic nanoparticles, Gemcitabine, Targeted drug delivery, Breast cancer, BIOMEDICAL APPLICATIONS, CANCER-THERAPY, PANCREATIC-CANCER, IN-VITRO, DELIVERY, BIODISTRIBUTION, ENDOCYTOSIS, RELEASE
Targeted delivery of anti-cancer drugs increase the efficacy, while decreasing adverse effects. Among various delivery systems, chitosan coated iron oxide nanoparticles (CsMNPs) gained attention with their biocompatibility, biodegradability, low toxicity and targetability under magnetic field. This study aimed to increase the cellular uptake and efficacy of Gemcitabine.