EUROPEAN JOURNAL OF PHARMACOLOGY, vol.784, pp.121-128, 2016 (SCI-Expanded)
Article / Article
EUROPEAN JOURNAL OF PHARMACOLOGY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Chitosan, Magnetic nanoparticles, Gemcitabine, Targeted drug delivery, Breast cancer, DELIVERY, BIOCOMPATIBILITY, BIODISTRIBUTION, ENDOCYTOSIS
Middle East Technical University Affiliated:
Targeted delivery of anti-cancer drugs increase the efficacy, while decreasing adverse effects. Among various delivery systems, chitosan coated iron oxide nanoparticles (CsMNPs) gained attention with their biocompatibility, biodegradability, low toxicity and targetability under magnetic field. This study aimed to increase the cellular uptake and efficacy of Gemcitabine.