Catalytic enantioselective addition of diethylzinc to aldehydes using aziridine based chiral ligands


BULUT A., ASLAN A., İZGÜ E. C. , Dogan O.

TETRAHEDRON-ASYMMETRY, cilt.18, sa.8, ss.1013-1016, 2007 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 18 Konu: 8
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.tetasy.2007.04.013
  • Dergi Adı: TETRAHEDRON-ASYMMETRY
  • Sayfa Sayıları: ss.1013-1016

Özet

The readily available ferrocenyl substituted aziridinylmethanol 1 (FAM-1) was used as a chiral catalyst in the diethylzinc addition reaction to aromatic and aliphatic aldehydes to give secondary alcohols in high yields and up to 99% enantiomeric excess at room temperature. The catalyst can be recovered and used without losing its activity. (c) 2007 Elsevier Ltd. All rights reserved.