Structural and functional damages of whole body ionizing radiation on rat brain homogenate membranes and protective effect of amifostine
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, vol.92, no.12, pp.837-848, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 92 Issue: 12
- Publication Date: 2016
- Doi Number: 10.1080/09553002.2016.1230237
- Journal Name: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.837-848
- Keywords: Amifostine, brain homogenate membrane, FTIR spectroscopy, ionizing radiation, lipid peroxidation, protein secondary structure, TRANSFORM INFRARED-SPECTROSCOPY, LIPID-PEROXIDATION, OXIDATIVE STRESS, SECONDARY STRUCTURE, ENDOTHELIAL-CELLS, WR-2721, IRRADIATION, INHIBITION, PROTEINS, DYNAMICS
- Middle East Technical University Affiliated: Yes
Abstract
Purpose: To investigate the effects of whole body ionizing radiation at a sublethal dose on rat brain homogenate membranes and the protective effects of amifostine on these systems at molecular level.