Structural and functional damages of whole body ionizing radiation on rat brain homogenate membranes and protective effect of amifostine


ÇAKMAK G., Severcan M., Zorlu F., Severcan F.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, cilt.92, sa.12, ss.837-848, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 92 Sayı: 12
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1080/09553002.2016.1230237
  • Dergi Adı: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.837-848
  • Anahtar Kelimeler: Amifostine, brain homogenate membrane, FTIR spectroscopy, ionizing radiation, lipid peroxidation, protein secondary structure, TRANSFORM INFRARED-SPECTROSCOPY, LIPID-PEROXIDATION, OXIDATIVE STRESS, SECONDARY STRUCTURE, ENDOTHELIAL-CELLS, WR-2721, IRRADIATION, INHIBITION, PROTEINS, DYNAMICS
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Purpose: To investigate the effects of whole body ionizing radiation at a sublethal dose on rat brain homogenate membranes and the protective effects of amifostine on these systems at molecular level.