Synthesis and Characterization of Hybrid Nanocomposites Based on Poly(2-chloroaniline)/Zinc Oxide Nanofiller for Antibacterial Studies Against Escherichia coli and Bacillus subtilis

Ahmad M. N., Farid M. F., Nawaz F., Anjum M. N., Qayyum M. A., Hussain T., ...More

JOM, vol.75, no.12, pp.5331-5340, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 75 Issue: 12
  • Publication Date: 2023
  • Doi Number: 10.1007/s11837-023-06144-3
  • Journal Name: JOM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, ABI/INFORM, Aerospace Database, Applied Science & Technology Source, Communication Abstracts, Compendex, Computer & Applied Sciences, INSPEC, Metadex, Civil Engineering Abstracts
  • Page Numbers: pp.5331-5340
  • Middle East Technical University Affiliated: Yes

Abstract

Antibacterial poly(2-chloroaniline)/zinc oxide nanocomposites (PoCA/ZnO NCs) were synthesized by chemical oxidative polymerization of 2-chloroaniline in the presence of ZnO nanoparticles (ZnO NPs). The colloidal method was employed to synthesize the ZnO NPs and further used to prepare the PoCA/ZnO NCs. The average particle size of ZnO NPs was determined to be around 68 nm by X-ray diffractometer using Scherer’s equation. The weight percentage of ZnO NPs to PoCA was varied to prepare the PoCA/ZnO NCs of different percentages (1–5%). Fourier transform infrared spectroscopy confirmed the structural aspects of PoCA/ZnO NCs, and scanning electron microscopic images showed the morphological features of nanocomposites. The optical properties were evaluated by ultraviolet–visible spectrophotometer. The UV–visible absorption of PoCA/ZnO NCs enhanced linearly with the increase in weight percentage of ZnO NPs. Moreover, the effect of ZnO NPs weight percentage on the antibacterial efficacy of PoCA/ZnO NCs was also investigated by the disc diffusion method against Escherichia coli and Bacillus subtilis. The bactericidal effect of PoCA/ZnO NCs was augmented with the increase in the weight percentage of ZnO NPs. The composites exhibited significant antibacterial inhibition zones against both gram-negative (5.1 mm) and gram-positive (5.0 mm) bacteria.